Prescription opioids

  • fentanyl
  • codeine
  • methadone
  • morphine
  • oxycodone
  • biodone
  • physeptone
  • hydromorphone
  • jurnista
  • buprenorphine
Are opioids a problem for you?
Get Help

What are opioids?

Opioids are natural drugs derived from the opium poppy or synthetic drugs, and have a depressant or sedating effect, causing the brain and central nervous system to slow down.

Learn more
Prescription opioids

Opioids have a strong pain-killing effect, therefore pharmaceutical opioids may be prescribed for medical conditions, particularly for acute or cancer pain management. Pharmaceutical opioids include morphine, oxycodone, fentanyl, hydromorphone, methadone, buprenorphine, tapentadol, tramadol and codeine.

Immediate effects can include

  • pain relief
  • feeling of wellbeing
  • reduced anxiety / calmness
  • sleepiness

Effects depend on...

How much you take, how often you have been using opioids (the longer you use, the more you may build up a tolerance to the effects), when you last took opioids, how pure the opioid is, your height and weight, your general health, your past experience with drugs, whether you use opioids on their own or with other drugs.

Opioids can come in the form of illicit or illegal drugs such as heroin or diverted pharmaceutical opioids used for non-medical purposes. Heroin or other illegally obtained opioids may be cut or mixed with other drugs or substances, it is therefore hard to know how strong the drug is and this can lead to accidental overdose or death. Using opioids in combination with other drugs (such as sleeping tablets, other sedatives and alcohol) can also lead to accidental overdose or death.

  • pupils of the eye become smaller
  • sweating
  • nausea or vomiting
  • shallow breathing

How opioids affects your body

Tap a body part to learn more of the effects Heroin places on your body.

Long term effects can include

  • overdose (the longer you use opioids, the greater your risk of overdose)
  • long-term and severe constipation
  • teeth problems
  • increased risk of contracting Hepatitis C and HIV
  • infertility (women)
  • impotence (men)
  • damaged veins from injecting
  • skin abscesses (sores with pus)
  • loss of appetite
  • irregular or no menstrual period (women)
  • heart and lung problems
  • infections of the blood

General Information

Are opioids a problem for you?

See full support list
  • ​​​​​​​​​​​​​​​​

    The Alcohol & Drug Information Service (ADIS) is a free and confidential counselling helpline for NSW residents with concerns around alcohol and/or drug misuse and is available 24 hours a day, 7 days a week. ADIS is staffed by professional counsellors who provide education, information, counselling, support and referrals to other appropriate services in NSW.

    Are you worried you could be drinking too much or consuming drugs in a way that has become a problem? Are you worried about your friends or family finding out and want to get help quickly and quietly? Are you worried about the drug use of someone close to you – maybe a family member or friend? Maybe you just want to know where someone can get help? 

    ADIS clinicians understand the difficulties of speaking out, seeking help and finding appropriate drug and alcohol treatment, and use their knowledge and experience to assist you and answer questions, such as:

    • How can I cut-down or stop my alcohol or drug use?
    • What help can I get?
    • Do I have to wait long to get help?
    • Can anyone ring ADIS?
    • Who do I talk to when I ring ADIS?
    • Will drug and alcohol treatments be difficult?
    • What is this drug doing to me?
    • What are the short and long term problems that could develop if I continue using?
    • Will ADIS tell anyone that I rang?
    • What can I expect when I ring?
    • Does ADIS record calls?

    You can call ADIS 24 hours a day, 7 days a week on 1800 250 015 or for Sydney Metropolitan 02 8382 1000 or alternatively you can start a Web Chat.

    ADIS Web Chat is available from Monday to Friday 8.30am – 5pm (including public holidays).

    ADIS also has a range of telephone lines offering specialised drug and alcohol information and support to particular groups.

    24 hour support line

    1800 250 015

    More about Alcohol and Drug Information Service (ADIS) NSW
  • ​​The Alcohol & Drug Information Service (ADIS) Web Chat is a live online conversation with a professional counsellor. The service is free, confidential and open to anyone affected by alcohol and other drugs, including people concerned about their own use, or about a family member or friend. Web chat is only available for people living in NSW.

    The service is provided by ADIS at St Vincent's Hospital, in partnership with the NSW Ministry of Health.

    What to expect

    • A counsellor will chat with you about your alcohol or other drug concerns
    • A counsellor can provide a referral or contact information for relevant alcohol and drug services in NSW
    • Our chat is confidential unless you disclose any intention to harm yourself or others.
    • WebChat is provided in English however if you prefer to speak in a language other than English we would be happy to arrange a telephone call with you through the Translating and Interpreting Service (TIS National). Please call the Alcohol and Drug Information Service on 1800 250 015 to arrange this.

    Emergency Assistance

    Call Emergency Services on 000 if you:

    • require urgent medical attention or
    • are in immediate danger or
    • are at risk of harming yourself or someone else.

    Monday to Friday 8.30am – 5pm (including public holidays)

    #;Web Chat

    More about ADIS Web Chat
  • Family Drug Support (FDS) provides support and assistance to families throughout Australia who are experiencing difficulty with a family member using alcohol or other drugs.

    FDS is a non-religious, non-judgemental and caring organisation of volunteers who have first-hand experience living with family members experiencing alcohol or drug dependency.

    FDS supports families by providing information about alcohol and other drugs, dependence and treatment options, while also helping families to overcome stigma and reduce self-blame, provide mutual support and help families build skills to strengthen their relationships.

    FDS provide a 24 hour, 7 days a week support line for families, support groups and meetings, the 'Stepping Stones' and 'Stepping Forward' courses, events and resources.

    Find out how FDS can help you.

    24 hour support line

    1300 368 186

    More about Family Drug Support (FDS)
  • The NSW Opioid Treatment Program (OTP), also known as opioid agonist treatment or opioid substitution treatment, provides pharmacotherapy and support services to people with an opioid dependence. Treatment may be provided as a short term measure to assist people to stop using other opioids, or for long term maintenance.

    The OTP is provided through public clinics, private clinics, general practitioners (GPs) and community pharmacies (find a pharmacy near you), and correctional facilities, and may be provided alongside other treatments such as counselling or residential rehabilitation. The pharmacotherapy medicines used in the NSW OTP are methadone, buprenorphine – inc​luding depot buprenorphine, given in an injection under the skin weekly or monthly – and buprenorphine-naloxone.

    1. What is opioid dependence?
    2. What are pharmacotherapy medicines?
    3. NSW Opioid Treatment Program
    4. Mixing OTP medicines with other drugs
    5. Driving Safety
    6. Talk to someone about OTP
    7. FAQs for OTP patients during COVID-19 (PDF)

    What is opioid dependence?

    When some people experience pain, both physical and or psychological, they may rely on opioids to make their body and mind feel better. People who are dependent on opioids find it very hard to stop using or cut down because of withdrawal symptoms. Stopping opioid use abruptly can lead to withdrawal symptoms, these can begin to occur within only a few hours after last use.

    Symptoms can include:

    • Sweats and chills
    • Sleeplessness and broken sleep
    • Uneasiness/anxiety
    • Feeling restless
    • Diarrhoea
    • Restless legs
    • Stomach and leg cramps
    • Nausea
    • Runny nose and eyes
    • Joint pain
    • Cravings (wanting opioids very badly)

    Some people may experience withdrawal after they have been on strong medicines prescribed by their doctor, such as oxycodone (Endone) or codeine. While others may experience it after using illicit drugs like heroin. Dependence is a medical condition, regardless of how people become dependent or what drug they use, everyone is entitled to treatment.

    What are pharmacotherapy medicines?

    Methadone, buprenorphine and buprenorphine-naloxone belong to a group of sedating and strong pain-killing drugs called opioids. Both methadone and buprenorphine are long-acting opioids, therefore only one dose per day is usually needed to prevent the uncomfortable symptoms of opioid withdrawal. Methadone and buprenorphine may also be prescribed by clinicians to patients to treat severe or chronic pain or in palliative care settings.

    The effects of methadone and buprenorphine can include relief from pain and a feeling of wellbeing, but can also cause nausea, sleepiness and long term use can have effects on male reproductive health, libido and cause sweating and constipation.

    Buprenorphine is effective at blocking the effect of other opioids, as it binds tightly to the opioid receptors in the brain. It comes in three different forms, a tablet (Subutex) or film (Suboxone) which are dissolved under the tongue, and a long acting injection (depot- Buvidal and Sublocade). For depot buprenorphine, injections last a week or a month.

    Buprenorphine may also be mixed with naloxone (buprenorphine-naloxone) to discourage people injecting.

    NSW Opioid Treatment Program

    The purpose of the OTP is to provide patients with access to treatment for opioid dependency, with a focus on improving patients’ health, wellbeing and engagement with their families and community.

    Patients can access treatment through public drug and alcohol services, private clinics, GPs and community pharmacies. The type of treatment they access will depend on the complexity of the care they need and their location.

    Treatment through public clinics is free for patients with the most complex care needs or for those needing supervised dosing.

    In many cases, patients can be treated in community settings such as private GP clinics with management of methadone or buprenorphine dispensed daily through community pharmacies.

    Most patients are required to start the program with a nurse or a pharmacist watching them take the methadone or buprenorphine every day. After some time patients may be able to have some of the medication to take at home, but this is only after the patient and the doctor are comfortable with how the treatment is progressing, and it is safe to do so.

    Long-acting depot buprenorphine does not require supervision because once the medication is injected it is slowly released over days or weeks, depending on the formulation.

    Patients and doctors will decide together what treatment plan and medication is best. Some patients may want to take the medication for a short amount of time, other patients may feel they need the medications for longer, each patients’ needs are different.

    Clinicians delivering the OTP are guided in practice by the NSW Clinical Guidelines: Treatment of Opioid Dependence.

    Only patients with opioid dependence are suitable for the OTP program. Similar opioid treatment programs are available in all states and territories.

    Mixing OTP medicines with other drugs

    Methadone and buprenorphine alone are not risky to take but it is necessary to understand how they interact with other sedating substances – particularly benzodiazepines and alcohol. There is a risk of over-sedation when taking sedating medications or alcohol while being treated with methadone.

    It is important that patients discuss with their clinicians (doctor, nurse or pharmacist) about all their prescriptions and their other substance use. Doctors can choose a different combination of prescription medication to reduce the risks.

    Driving Safety

    It is not risky to drive when on a stable dose of methadone or buprenorphine, as long as you are not taking other sedating substances or drugs at the same time.

    In the first two weeks of buprenorphine and first four weeks of methadone treatment, and any time where the dose is changed by 5mg or more, you are strongly advised NOT to drive or operate heavy machinery.

    For more information, visit drivingsafety.com.au 
    or
    Download the Driving Safety and Medicines Fact Sheet

    Pregnancy and child safety

    Babies and children can die from taking methadone or buprenorphine. It is important that any takeaway doses are stored in a locked cupboard or drawer, and to never take the medicines in front of children. Depot buprenorphine is a good alternative for parents, as there are no takeaway doses and therefore no chance of exposing children to the medicines.

    Methadone and buprenorphine must never be given to babies or children, unless prescribed to them. If a child has taken it call 000 (triple zero) immediately.

    If you are dependent on opioids and pregnant, or planning to become pregnant, it is important you consider getting treatment for opioid dependency. Substance Use in Pregnancy and Parenting Service (SUPPS) can coordinate treatment, call Alcohol and Drug Information Service (ADIS) on 1800 250 015, for counselling and referrals 24 hours a day, 7 days a week.

    Talk to someone about OTP

    The Opioid Treatment Line (OTL) is a phone based service that provides opioid pharmacotherapy information, referrals, advice and a forum for pharmacotherapy or treatment concerns. OTL assists people who want to know more about the system of opioid treatment in NSW, including how to get onto a program, and what they should expect from clinics and doctors providing the service.

    For more information contact the Opioid Treatment Line (OTL) on 1800 642 428, Monday to Friday 9.30am to 5.00pm with temporarily extended service hours to include 9:30am - 2:00pm on weekends and public holidays to support Covid-19 related queries.​​

    For information from a consumer led organisation, contact NSW Users and AIDS Association (NUAA).

    NEW! Consumer guideline series is available online through NUAA.

    For free and confidential advice call the Alcohol and Drug Information Service (ADIS) on 1800 250 015. Counsellors are available 24/7 to provide information, referrals, crisis counselling and support. Or start a Web Chat with an ADIS counsellor online Monday to Friday, 8.30am – 5pm.



    More about Opioid Treatment Program
  • Families, friends and loved ones can play a critical role in the recovery of people who experience alcohol and other drug problems, however they are often focused on the needs of others while they neglect their own their own health and wellbeing.

    The Family and Friend Support Program (FFSP) is an online cognitive behavioural therapy program to support people who are caring for or supporting someone with alcohol and other drug use issues.

    FFSP is based on a series of modules and includes information and activities on how families and friends can help their loved ones, with a specific emphasis on the person providing the support and their often unmet needs. The program is also suitable for health professionals.

    For information on how to start a conversation with your loved one about their alcohol and or other drug use, tips on how to look after yourself and other resources visit our For Families mini-site.

    Cost

    The program is free and available 24 hours a day, 7 days a week. 

    Please note that for Health Professionals there are costs involved in the 5-step training. Details about the training can be found on the Health Professionals portal in FFSP (under the icon 5-step).

    The FFSP is supported by funding from the Australian Government Department of Health.

    More about Family and Friend Support Program
  • PeerLine is confidential service run by the NSW Users and AIDS Association (NUAA). NUAA works to improve the health, welfare and dignity of people who use drugs. 

    PeerLine is a free, confidential peer supported telephone service for people who use drugs, who are on the Opioid Treatment Program or seeking treatment. Trained peers will help you with information, advice and advocacy

    NUAA-PeerLine-FullLogo.png

    PeerLine is available from 9.00am to 5.00pm Monday to Friday (excluding public holidays).

    Call for free on 1800 644 413 or email peerline@nuaa.org.au to connect.

    Monday to Friday 9am – 5pm

    1800 644 413

    More about NUAA PeerLine
  • The NSW Needle and Syringe Program (NSP) is an evidence-based public health program that aims to reduce the transmission of infections such as HIV and hepatitis C among people who inject drugs. NSP outlets provide sterile injecting equipment such as needles and syringes, Fitpacks and other injecting equipment (such as swabs, water, spoons and cotton balls) as well as disposal facilities free of charge.

    NSP outlets are staffed by specialist workers who provide access to sterile injecting equipment, promote safe disposal practices and facilitate referrals to health, welfare and community services as needed. NSP outlets may also be able to assist with testing for blood borne viruses such as HIV and hepatitis C. You may not even require a blood test such as with the Dried Blood Spot (DBS) test. Ask your NSP staff member or visit dbstest.health.nsw.gov.au for more information. 

    Who is the program for?

    The NSP is for people who inject drugs to avoid contracting or transmitting blood borne diseases and to provide a place for safe disposal of sharps containers (needles and syringes).

    NSP Outlets in NSW

    To help the community access the program, an interactive map has been developed listing all public NSP outlets across NSW. Use the map below to find your nearest NSP outlet or refer to the NSP listing by suburb page for details.

    If you would like further information and/or advice call the Alcohol and Drug Information Service (ADIS) on 1800 250 015.

    More about NSW Needle and Syringe Program (NSP)
Your Room > A-Z of Drugs > Prescription opioids