Nitazenes

  • Etazene
  • Isotonitazene
  • Metonitazene
  • Protonitazene
  • Protonitazepyne (N-pyrrolidino protonitazene)
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​Quick facts about nitazenes

  • ​​​​​​​​​​​​​​​​​​​​​Nitazenes are extremely strong synthetic opioid drugs. They can be up to 500 times stronger than heroin.
  • There is no known safe dose of nitazenes
  • The strength and purity of nitazenes can vary even in the same batch.
  • Nitazenes have been found in many parts of the illicit drug supply including MDMA, heroin, cocaine, benzos and ketamine.
  • There is a very high risk of overdose if you take nitazenes – always carry naloxone
  • Fentanyl test strips cannot detect nitazenes

NSW Health puts out public drug warnings when there are high-dose drugs or dangerous ingredients/adulterants in circulation.

Here is the latest nitazenes drug warnings. Nitazenes causing severe opioid overdoses in NSW​ - May 2024

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Nitazenes
Nitazenes

Isotonitazene

C23H30N4O3

Some nitazenes recently found in local and international drug markets are:

  • Etazene (etodesnitazene)
  • Isotonitazene
  • Metonitazene
  • Protonitazene
  • ​​Protonitazepyne (N-pyrrolidino protonitazene)​

Nitazene strength is highly variable. People have believed they were taking one type of nitazene, but actually took a much stronger type, causing them to overdose.​​

Immediate effects

  • Euphoria, feeling relaxed
  • Short term pain and stress relief
  • Nausea and vomiting
  • Fever and sweating

Effects can depend on...

  • The amount used and its strength
  • The method used, such as snorting, swallowing, smoking, vaping or injecting
  • People's size, weight and general health
  • Whether combined with other drugs
  • User tolerance​

  • Drowsiness
  • Slowed and shallow breathing and heart rate
  • Small pupils (pinpoint pupils)
  • Sleepiness, drowsiness and coma

How nitazenes affect your body

Tap on a body part to learn more of the effects nitazenes places on your body

Long-term effects

  • Tolerance (needing more of a drug to feel the same effects)
  • Dependence
  • Long-term and severe constipation
  • Heart and lung problems

General information

 

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